产品货号：
Z26197
中文名称：
SAPAP3/DLGAP3抗体
英文名称：
Anti-SAPAP3/DLGAP3 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-SAPAP3/DLGAP3 Antibody |
| 指标别名 | DAP 3;DAP3;DLGAP3;PSD 95/SAP90 binding protein 3;SAPAP3 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,IHC,IF |
| 基因名称 | DLGAP3 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | SAPAP3 antibody was raised against a 18 amino acid synthetic peptide from near the carboxy terminus of human SAPAP3.The immunogen is located within the last 50 amino acids of SAPAP3. |
| 计算分子量 | 106kDa |
| 成分 | SAPAP3 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | SAPAP3 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | SAP90/PSD-95-associated protein 3 (SAPAP3,also known as DLGAP3) is a member of a protein family whose members specifically interact with PSD-95/SAP90,a membrane-associated guanylate kinase localized at postsynaptic density (PSD) in neuronal cells.Like the other SAPAP proteins,SAPAP3 is thought to be an adaptor protein that also interacts with different synaptic scaffolding proteins,cytoskeletal and signaling components,such as focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2).Both SAPAP3 protein and mRNA are targeted to dendrites,whereas SAPAP1,-2,and -4 mRNAs are detected mainly in cell bodies.Recent experiments have suggested that SAPAP3 may be involved in obsessive-compulsive disorder (OCD),as mice lacking SAPAP3 exhibited OCD-like symptoms which could be relieved by lentiviral-mediated selective expression of SAPAP3 in the striatum of SAPAP3-mutant mice.At least two isoforms are known to exist. |
| Uniprot ID | O95886 |
| 基因名全称 | Discs,large (Drosophila) homolog-associated protein 3 |
| 蛋白名全称 | Discs,large (Drosophila) homolog-associated protein 3 |
| 推荐稀释比 | SAPAP3 antibody can be used for detection of SAPAP3 by Western blot at 1μg/mL.Antibody can also be used for immunohistochemistry starting at 2.5μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in rat samples;Immunohistochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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